Hit Finding


For the identification of the first active compounds at a new target we use three different approaches.

1. The structure based approach contains virtual screening and the synthesis of virtual hits or a directed small library considering the customers' needs.

2. The ligand based approach includes computational similarity search, synthesis of reasonable analogues or mimetics of the natural ligand and the development of a pharmacophore model.

virtual Hit Finding

Experimental Hit Finding


3. If the target enzyme is available a high throughput screening assay will be developed. For the screening exclusively synthesised or commercially available compound libraries will be used.

Experimental Hit Finding


Product Sheet: Hit Identfication